We conducted a prospective and observational study in a teaching hospital in France during 8 months in ICU. All patients with sepsis requiring vasoactive drugs were included. We recorded mottling score and skin temperature with a thermic camera of the 5 mottling areas around the knee (temperatures recorded with FLIR software) at bedside. Measures were performed at ICU admission (H0) and six hours after initial resuscitation (H6).