Sustainability and sustainable development are concepts that often surround land planning and development issues. Incorporating concrete sustainability principles into land use planning can be a challenge as sustainability tends to be an abstract concept in which several issues are intertwined. This thesis attempts to examine two measures, one ecological measure and one human health measure, and combine them so that they can be incorporated into land use decisions rooted in sustainability principles. Specifically, these measures are quality adjusted life years, which measure the health impact of air quality reductions, and net primary productivity, which measures the carbon absorbing potential of flora. A prototype methodology is then created which integrates these measures into a framework that can be followed during the decision-making process. As a test, this prototype methodology is applied to two counties in North Carolina to determine feasibility issues and limitations. Results indicate that this methodology can be useful in determining optimal locations for future land development in regards to net primary productivity and air quality. Feasibility can be an issue due to the potentially large percentage by which development must decrease in some cases in order to achieve a target QALY. This is due in part to the overestimation of decline in QALY's associated with development, which is a result of the precautionary assumptions built into the Hazard Index as this is used within the QALY equation.