Research Question: In adult stroke victims, how does quality of sleep affect stroke recovery with regard to speech and language? Background: Sleep apnea and other forms of sleep disturbance are common among patients who have suffered from stroke. These indicators of poor sleep may impact stroke recovery outcomes. Past studies have linked poor sleep quality to worse functional outcomes in stroke patients, but few have investigated the direct impact of sleep on speech and language in this population. This relationship may carry clinical implications about the sleep needs of stroke patients who are receiving speech and language therapy during their rehabilitation. Methods/Proposed Methods: A systematic review of articles investigating the link between sleep, stroke, and speech and language outcomes was conducted to address the research question at hand. The reviewers searched the PubMed database with a string of terms relevant to sleep, stroke, speech, and language, including a set of motor and cognitive terms which may underlie speech and language function. Based on relevance, articles were included by the three reviewers, first through a triple title and abstract review and second through a triple full text review. Reviewer reliability for the title/abstract and full text reviews were 88% and 84%, respectively. Then, the reviewers double appraised the included articles to determine their evidence level and discussed any appraisal discrepancies to establish consensus. Finally, they extracted relevant data from the articles deemed valid and reliable for use in evidence synthesis. Anticipated Results: The initial search returned 147 articles, which was reduced to 26 results by title/abstract review and to 19 finalized inclusions by full text review. The reviewers anticipate that results of the articles meeting inclusion criteria will indicate an association between suboptimal quality and amount of sleep with worse motor learning and cognitive outcomes in stroke patients. Discussion: If the results support an association of sleep quality and/or duration with motor and cognitive function in stroke patients, the reviewers will interpret that as indicating that sleep has an impact on speech and language outcomes post-stroke. Such results would support the prioritization of sleep quality during stroke rehabilitation. Conflicts of Interest: The reviewers have no intellectual or financial conflicts of interest.