Whole brine resting-state fMRI data from 227 healthy adults between 18 and 78 years old acquired at a 3T clinical MRI scanner. The tar file contains 227 compressed nifti files. The 1st alphabet in the file names indicates the gender of the volunteers (f for female and m for male). The 2nd and 3rd digits indicate the age of volunteers. The remaining alphabets are randomized to encode individual subjects. The original images were reconstructed into dicom format and converted into nifti file format.