The present study provides a first overview of the developmental, physiological, and molecular mechanisms occurring in maraena whitefish in response to culturing procedures and to aquaculture related stressors. Maraena whitefish was found to be a suitable fish species for the establishment of a local, economic and sustainable aquaculture. However, it was shown that the stocking density, the temperature, and the water quality (reagarding pathogenic contaminations) must be carefully adjusted within optimal ranges, to avoid adverse effects on this sensitive species.