This dissertation deals with the identification of suitable indicators for monitoring the health status of intensively farmed pikeperch, a fish species of great importance for the diversification of European aquaculture. Suitable candidate genes were identified to investigate potentially inadequate husbandry conditions as well as ontogenetic processes at the transcriptional level. Furthermore, it could be shown that reduced oxygen saturation (40%) and increased water temperatures (25 °C) do not lead to severe stress responses in juvenile fish.