Interatomic potentials for the Ni-Al-Ti system has been developed based on the second nearest-neighbor modified embedded-atom method (2NN-MEAM) formalism. Atomistic simulations using the Ni-Al-Ti ternary potential validate that the potential can be applied successfully to atomic-scale investigations to clarify the effects of titanium on important materials phenomena (site preference in γ′, γ-γ′ phase transition, and segregation on grain boundaries) in Ni-Al-Ti ternary superalloys.