A spectral neighbor analysis potential for Ni-Mo chemistries. The potential is trained against diverse and large materials data, including undistorted ground state structures for Ni, Mo and the two binary intermetallics Ni3Mo and Ni4Mo; distorted structures constructed by applying different strains to a bulk supercell; surface structures of elemental structures; ab-initio molecular dynamics (AIMD) simulated random structures at different temperatures; alloy structures constructed by partial substitution of supercells of the bulk fcc Ni with Mo and the bulk bcc Mo with Ni. The potential gives accurate predictions of structural energies, forces, elasticity, lattice parameters, vacancy migration barrier, equation-of-state, phonon, free energies, melting point, surface energies, and Ni-Mo phase diagram.