Machine tools have to reach high levels in accuracy and speed. For the detailed analysis of the machine dynamics with respect to these properties, a machine model has to include the main concepts of multibody dynamics and feedback control systems. With such a model available, dynamic investigations in frequency-and time-domain can efficiently be done. This work shows how to build a multibody system, and its integration in the feedback control loop. A control system model being coupled with high DOF structural model permits the simulation of interactions between machine tool manipulators and its spatial effects at the TCP (Tool Centre Point) including the position dependency of the properties. The available results and analysis functionalities of a proprietary implementation in a simulation environment are explained and illustrated.