2 Citations 275 Views 53 Downloads
Here we present images of loop-mediated isothermal amplification (LAMP)
and optimized Cap-iLAMP (capture and improved loop-mediated isothermal
amplification). Cap-iLAMP combines a hybridization capture-based RNA
extraction of gargle lavage samples with an improved colorimetric RT-LAMP
assay and smartphone-based color scoring. Cap-iLAMP is compatible with
point-of-care testing and enables the detection of SARS-CoV-2 positive
samples in less than one hour. The sensitivity is 97% and the specificity
is 99%.
275 views reported since publication in 2020.