The presentation corresponds to a IUPAC WorldFair Chemistry Webinar. The presentation aims at presenting in 5mn the type of chemistry data that are used in astrophysics, how we annotate those data, how we manipulate those data, what are the challenges and the issues linked to FAIR implementation, and what could be the collaboration with IUPAC. The PDF are uploaded at DOI 10.5281/zenodo.7101252 IUPAC : https://iupac.org/worldfair-global-cooperation-on-fair-data-policy-and-practice/ and https://iupac.org/project/2022-012-1-024/ VAMDC: https://vamdc.org