Open Science is the movement to make scientific research (including publications, data, physical samples, and software) and its dissemination accessible to all levels of society, be they researchers, amateurs, or professionals. [1] As a working model for scientific activity, Open Science has the potential to promote greater economic and social development in Latin America, favouring the efficient and safe utilization of the resources dedicated to funding science and facilitating the processes for knowledge transfer and dissemination in a region rife with challenges and inequities. The incorporation of transparent, collaborative, and open scientific practices also improves the quality of results, their impact, and their reproducibility. This transparency and accessibility strengthen the ability to translate scientific advances into innovations and allow the interaction of the scientific world with open innovation systems that need to be strengthened to facilitate the creation of wealth and strengthen productivity and the accumulation of human capital in our society. The draft text of the UNESCO Recommendation on Open Science highlights the five key pillars on which it is supported: open scientific knowledge, open science infrastructure, scientific communication, open engagement of societal actors, and open dialogue with other knowledge systems. [2] The current dimensions and characteristics of scientific activity are such that its productivity is contingent on certain key factors such as access to global collaboration networks, the effective management of data and scientific publications (e.g., the possibility of searching, accessing, interacting with, and reusing these data and the related scientific publications), computing power, connection speed, and the availability of shared research infrastructures. This collection of necessary infrastructures serves as the base for the digital ecosystem needed to support and promote Open Science. Latin America has a long tradition in this area that can provide the foundations to develop important leadership in the deployment and strengthening of these ecosystems, increasing our ability to incorporate ourselves into existing collaborations and to promote the development of new scientific collaborations. This document proposes a vision for this digital Open Science ecosystem that we must finish building in an orderly manner, analysing its components and interactions, while suggesting possible courses of action for ...