Within the realm of TRANSFORM, Lombardy Region commits to render S3 more inclusive and transparent, ensuring that citizens’ voices are heard, and opinions are taken into account in setting up key regional R&I policies (participatory research and innovation, agenda setting). This video describes the first stream of deliberative engagement conducted in Lombardy within the TRANSFORM project: sharing their experiences and opinions on personal and territorial needs, citizens contribute to shape regional R&I priorities. More than 1000 people leaving in the region are engaged thanks to a structured participatory agenda setting pilot exercise, which is held entirely online (due to the COVID-19 emergency) combining a mix of quantitative (a survey administered to a representative sample of the Lombardy population) and qualitative (a deliberative workshop) methods. The citizens' input collected from citizens has been included in the regional Three Years’ Strategic Plan for Research, Innovation, and Technology Transfer. This project has received funding from the European Union's Horizon2020 research and innovation programme under grant agreement No 872687. This video reflects only the authors' view. The European Research Executive Agency (REA) and the European Commission are not responsible for any use that may be made of the information it contains.