This dataset include the raw data of our experience after building a bespoke laboratory to control critical areas by pooling samples of saliva. From August 2020 to February 2022; 928,528 individual self-samples of saliva were processed in 52,580 pools, 4,935 of which were positive and helped us detect 5,806 nonsymptomatic individuals. The dataset was collected directly from the laboratory information system and was processed to delete the columns with sensitive information. The Dataset was charged as XLSX file and only need a compatible software. To facilitate the understanding of the data set, which uses the Galician language and an internal nomenclature of our laboratory, we include a sheet named "description" and a README file in which it defines the terms used and their equivalence with those used in the article.