The objective was to evaluate the impact of a municipal strategy to reduce Ae. aegypti in Asunción focused on the management of household bulky waste. To estimate the result, the Difference in Difference (DID) method was used. For the baseline, a simple random sampling of 324 households was carried out. The intervention implemented by the local government in an area with 180,000 residents, contributed to the collection of the equivalent of 14 kilos of bulky waste per inhabitant, given an idea of the magnitude of the problem. For the evaluation survey, 2.5 to 4 years after the intervention, 120 households were randomly selected, of which 60% had not been intervened (control households) and 40% had been intervened. As a result, a significant reduction was achieved in the total number of large solid waste found in the homes that were the object of the intervention. The differentiated collection was used mainly by those households that had a large number of large solid waste (DID of -55%), but not to get rid of all of these objects, but only a part. The data present no evidence of change in the percentage of households with breeding containers between the intervention and control groups.