This Figshare page contains a video abstract and summary slide.
DisclosuresFunding Open access was funded by Sanofi and Regeneron Pharmaceuticals, Inc. The current research was sponsored by Sanofi and Regeneron Pharmaceuticals, Inc. ClinicalTrials.gov Identifier: NCT03054428. The study sponsors participated in the study design; collection, analysis, and interpretation of the data; writing of the report; and the decision to submit the article for publication. Medical writing/editorial assistance was provided by Carolyn Ellenberger, PhD, of Excerpta Medica, funded by Sanofi Genzyme and Regeneron Pharmaceuticals, Inc. Potential Conflicts of Interest Amy S. Paller has served as an investigator and/or consultant for AbbVie, Amgen, AnaptysBio, Asana, Dermavant, Dermira, Eli Lilly, Galderma, Forte, Incyte, Janssen, LEO Pharma, Matrisys Bioscience, Menlo Therapeutics, MorphoSys/Galapagos, Novartis, Pfizer, Regeneron Pharmaceuticals, Inc., and Sanofi. Ashish Bansal, Zhen Chen, Paola Mina-Osorio, Yufang Lu, Xinyi He, Mohamed Kamal, Neil M. H. Graham, Marcella Ruddy, and Abhijit Gadkari are employees and shareholders of Regeneron Pharmaceuticals, Inc. Eric L. Simpson served as an investigator and/or consultant for AbbVie, Boehringer Ingelheim, Dermavant, Eli Lilly, Galderma, Forte, Incyte, Kyowa Hakko Kirin, LEO Pharma, Merck, Menlo Therapeutics, Pfizer, Pierre Fabre Dermo Cosmetique, Regeneron Pharmaceuticals, Inc., Sanofi Genzyme, and Valeant. Mark Boguniewicz served as an investigator and/or consultant for Regeneron Pharmaceuticals, Inc. and Sanofi Genzyme. Andrew Blauvelt served as a consultant and investigator for AbbVie, Aclaris, Akros, Allergan, Almirall, Amgen, Arena, Boehringer Ingelheim, Bristol-Myers Squibb, Celgene, Dermavant, Dermira, Eli Lilly, Galderma, Genentech/Roche, GlaxoSmithKline, Janssen, LEO Pharma, Meiji, Merck Sharp & Dohme, Novartis, Pfizer, Purdue Pharma, Regeneron Pharmaceuticals, Inc., Revance, Sandoz, Sanofi Genzyme, Sienna Pharmaceuticals, Sun Pharma, UCB Pharma, Valeant, and Vidac and served as a speaker for Janssen, Regeneron Pharmaceuticals, Inc., and Sanofi Genzyme. Elaine C. Siegfried served as a principal investigator for AbbVie, Boehringer Ingelheim, Celgene, Dermavant, Dermira, Eli Lilly, LEO Pharma, Novan, Novartis, Pfizer, Regeneron Pharmaceuticals, Inc., Sanofi, and UCB and as an investigator for Allergan, Eli Lilly, Janssen, Mayne, Regeneron Pharmaceuticals, Inc....
DisclosuresFunding Open access was funded by Sanofi and Regeneron Pharmaceuticals, Inc. The current research was sponsored by Sanofi and Regeneron Pharmaceuticals, Inc. ClinicalTrials.gov Identifier: NCT03054428. The study sponsors participated in the study design; collection, analysis, and interpretation of the data; writing of the report; and the decision to submit the article for publication. Medical writing/editorial assistance was provided by Carolyn Ellenberger, PhD, of Excerpta Medica, funded by Sanofi Genzyme and Regeneron Pharmaceuticals, Inc. Potential Conflicts of Interest Amy S. Paller has served as an investigator and/or consultant for AbbVie, Amgen, AnaptysBio, Asana, Dermavant, Dermira, Eli Lilly, Galderma, Forte, Incyte, Janssen, LEO Pharma, Matrisys Bioscience, Menlo Therapeutics, MorphoSys/Galapagos, Novartis, Pfizer, Regeneron Pharmaceuticals, Inc., and Sanofi. Ashish Bansal, Zhen Chen, Paola Mina-Osorio, Yufang Lu, Xinyi He, Mohamed Kamal, Neil M. H. Graham, Marcella Ruddy, and Abhijit Gadkari are employees and shareholders of Regeneron Pharmaceuticals, Inc. Eric L. Simpson served as an investigator and/or consultant for AbbVie, Boehringer Ingelheim, Dermavant, Eli Lilly, Galderma, Forte, Incyte, Kyowa Hakko Kirin, LEO Pharma, Merck, Menlo Therapeutics, Pfizer, Pierre Fabre Dermo Cosmetique, Regeneron Pharmaceuticals, Inc., Sanofi Genzyme, and Valeant. Mark Boguniewicz served as an investigator and/or consultant for Regeneron Pharmaceuticals, Inc. and Sanofi Genzyme. Andrew Blauvelt served as a consultant and investigator for AbbVie, Aclaris, Akros, Allergan, Almirall, Amgen, Arena, Boehringer Ingelheim, Bristol-Myers Squibb, Celgene, Dermavant, Dermira, Eli Lilly, Galderma, Genentech/Roche, GlaxoSmithKline, Janssen, LEO Pharma, Meiji, Merck Sharp & Dohme, Novartis, Pfizer, Purdue Pharma, Regeneron Pharmaceuticals, Inc., Revance, Sandoz, Sanofi Genzyme, Sienna Pharmaceuticals, Sun Pharma, UCB Pharma, Valeant, and Vidac and served as a speaker for Janssen, Regeneron Pharmaceuticals, Inc., and Sanofi Genzyme. Elaine C. Siegfried served as a principal investigator for AbbVie, Boehringer Ingelheim, Celgene, Dermavant, Dermira, Eli Lilly, LEO Pharma, Novan, Novartis, Pfizer, Regeneron Pharmaceuticals, Inc., Sanofi, and UCB and as an investigator for Allergan, Eli Lilly, Janssen, Mayne, Regeneron Pharmaceuticals, Inc....