Additional file 1. Supplemental images for IOSE-121 normal cells or OV2008 tumor cells incubated in medium alone or in presence of chitosan for 1 h. Also images of IOSE-121 normal cells or OV2008 tumor cells incubated in presence of chitosan and gray value intensity evaluated around the cells. In addition, images of OV2008 incubated with DDS at 10 min and 1 h at three different concentrations of paclitaxel and four images showing tumor cells OV2008 and normal cells incubated with the DDS using 15 min pulse treatment and evaluated at 15 min and 24 h.