Additional file 8: Fig. S8 GeneMANIA network summary predictions GeneMANIA network generated using Ingenuity Pathways Analysis gene predictions. The network highlights potential interactions between Phospho1 and related osteoblast genes involved in the glucose metabolic process, encompassing; glucose transport, insulin receptor signalling, response to insulin and cellular response to insulin stimulus. Query genes (black) with the exception of Spic and Runx2 which were inputted manually, other genes (grey) were generated by the programme using a large set of inbuilt functional association data. Node size are based on GO terms. Network line colour corresponds to interaction: purple = co-expression, pink = physical interactions, blue = co-localisation, green = shared protein domains orange = predicted, grey = other.