Copyright information:Taken from "Refinement of a chimpanzee pericentric inversion breakpoint to a segmental duplication cluster"Genome Biology 2003;4(8):R50-R50.Published online 15 Jul 2003http://www.ncbi.nlm.nih.gov/pmc/articles/PMC193642.Copyright © 2003 Locke et al.; licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original URL. Probe -I was used to demonstrate a 104 bp RFLP distinguishing the intact (548 bp band) and duplicated (444 bp band) loci in the human genome (lane 1). A single band - corresponding to the intact locus - is seen in PTR, PPA and GGO (lanes 2 and 3, 4 and 5, 6 and 7, respectively), indicating that the duplication of was a recent human-specific event and that therefore the gene is single copy in the PTR genome.