Additional file 2: Table S1. Features of genes used in sysSVM2. Table S2. Cohorts and genes used in the study. Table S3. Application of sysSVM2 to TCGA samples. Table S4. Driver predictions in 7646 TCGA samples. Table S5. Gene set enrichment analysis of TCGA predictions. Table S6. sysSVM2 driver predictions in PCAWG osteosarcomas.