The aim of the research is to discuss, within the framework of the Architectural Utopias of the 60s, the concept of Space colonization, declining it in the ephemeral use of megastructures. The main role given by the study to the English group Archigram wants to highlight how their experimental proposals are not so far from our reality and how their conceptual framework perfectly matches with the requirements. The rising of the idea of space colonization got a reserved spot in the scientific research since 1969, when the first human footprints were left on the lunar soil, and analyzing the current project proposals we can define some common points that we can highlight and confront with Archigram. The English group is given a role of absolute European centrality in the field of Utopian Megastructuralism, as their main concept ideas, were to break from the past in order to “invent and develop an ex-novo modern city, as huge tumultuous, agile and dynamic construction site in each of his part” and not less important, a vision of the city made of components, interchangeable and updatable where the dimension of time plays an important role given the indetermination and fluency in scientific and social evolution. The name itself is a representation of immediacy, as the group wanted an architecture that was important, urgent and rapid at the same time, like a telegram, from which the payoff “Archi(tecture...tele)gram”. One of Archigram’s accomplishments had been to reorient architecture toward changing social and ideological patterns. The innovation of Archigram stands also in reconsidering the urban fabric and the city from the inhabitants point of view and their conditions: the surrounding environment usually characterized by buildings in their physical mass (hardware) should be imagined as something flexible and upgradable, non-static (software) according to the users’ needs. And so is the un-explored field of living on new planets. The final question should be, Can Archigram proposals be the solutions for the colonization of new planets?