The Science and Technology Facilities Council (STFC) is a world leading multidisciplinary science and technology organisation. Its facilities provide a range of research techniques using neutrons, muons, lasers and x-rays, and high performance computing and complex analysis of large data sets. In Wales, a regional pilot beamline-bridging centre, a partnership between an academic institution (Swansea University) and a research and technology organization (RTO, TWI Wales) has been setup to develop new relationships with industry partners in the region, leading to new engagements with STFC facilities (Fig.1). This will generate impacts for the company, people, and wider society in Wales. Impact could be new products, improved understanding of manufactured products, improved processing and materials development, or new research into medical and health interventions. This partnership approach with industry in the region will increase the uptake of STFC facilities, in particular Diamond and ISIS, and the Central Laser Facility. The regional centre will attract a multidisciplinary research base from throughout Wales and increase their exposure to the UK’s world- class research facilities. The centre will be a hub for regional industry, generating impact through industrial research and development that was previously impossible or highly unlikely without this pilot bridging project. There are challenges to engaging small-to-medium sized enterprises (SMEs) with large-scale scientific facilities such as those operated by STFC. The perceived gap between applied demand-led manufacturing, and seemingly high-level unattainable science presents a communication and translation challenge. In addition, SMEs have limited resource for research-based approaches to product development/improvement, coupled with constraints on staff time and capabilities to capture and analyse potentially large data. The regional centre, embedded locally, will bridge this perceived gap via a partnering approach, teaming the local company with beamline-industry-bridging officers (BIBOs) to identify the challenges, scope solutions, design experiments, carry out lab-based feasibility studies, and if beneficial, identify STFC facilities which could benefit the company. Once data is collected, this relationship will continue, with the BIBO’s expertise and regional proximity to the company enabling the subsequent advanced analyses. This process will increase the likelihood of implementation of the f...