Additional file 3. Figure S3. Immunohistomorphometric analyses of atherosclerotic lesions in the PT of ApoE-/- and GDF15-/-ApoE-/- mice after 20 weeks of CED. Expression of the pro-inflammatory markers COX-2 (A and C) and IL-6 (B and D). L: lumen; Nc: necrotic core; TA: tunica adventitia. Black arrow: positive immunoreactivity; magnification: scale bar 100 µm.