Additional file 2: Fig. S2. Phenotypic characterization of T cells, expressing TLR, and B cells gated on larger and more granular cells from CCM patients. In (A), the gating strategy and identification of different larger and more granular lymphocytes according to the expression of CD3, CD19, CD14, CD16 and CD45RO markers. In (B), the mean percentage of naïve (CDR5RO−CD62L+), central memory (CM, CDR5RO+CD62L+), effector memory (EM, CDR5RO+CD62L−) and terminally differentiated effector memory (TEMRA, CD45RO−CD62L−) T cells from CCM patients was determined and significance calculated by comparing the proportion of different T cell phenotypes according CD45RO and CD62L expression (Kruskal–Wallis test and Dunn’s test).