Additional file 4: Fig S4. P300/CBP and BET inhibition have disparate effects on steady-state and IFNγ-inducible transcription. (A) Venn diagram overlap of genes down-regulated following 3 h treatment with JQ1 and A-241 (P-value < 0.05, log2 fold-change < -1 relative to DMSO) in AT3 cells. (B) Row-scaled heatmap of normalized gene expression values for (log2 counts per million) of IFNγ-induced genes following treatment of AT3 cells with IFNγ ± A-241 or A-485, respectively. (C) Normalized counts (log2 counts per million) of Stat1 and Tap1 following IFNγ ± A-241. (D) Normalized counts (log2 counts per million) of IFNγ-induced genes following treatment of AT3 cells with IFNγ ± JQ1 or IFNγ ± A-241. *p < 0.05, ****p < 0.0001 t test.