Rice (Oryza sativa L.) is a staple food for half of the world's population. Consequently, the search of solutions to prevent rice losses by insect infestation is a priority subject for the rice value chain. The rice weevil and the rice moth are key insect pests causing indoor infestations, as part of a set of other insect species, which chew and bore the rice grains. The most relevant species are Sitophilus oryzae, Rhyzopertha dominica, and Sitotroga cerealella. To reduce insect infestations, chemicals are usually applied during storage, fumigations being the most used. However, those chemicals produced residues as contaminants which may compromise the quality of rice and its derivates. With the climate change scenarios, it is expected an increase of insect infestations, due to temperature and moisture changes, but also an increase on resistance issues caused by excessive use of fumigation. Furthermore, public regulators are also setting lower residue limits for synthetic pesticides, setting precise targets for reducing pesticide use in plant production, and directly encourage the use of alternatives. The risk for human health, the emergence of insects resistant to the chemical insecticides1,2, the imposed regulations and the growing consumer concerns on food residues, compromise and all the rice chain and promote the development of alternative solutions to control insect infestations in stored grains. The practical solutions already available can be applied at industrial scale includes the atmosphere control and it is important to eliminate oxygen, since without oxygen there is no development of insects. The packages must be hermetic to prevent air entry, and vacuum packaging can be used, or packaging with inert gas such as nitrogen and carbon dioxide. These atmospheres are safe and ecologically accepted for insect control and have been proposed as viable alternative treatments. Also, the application of radiofrequency waves can be used in the disinfestation of insect pests for a short period of time, being able to eliminate the offspring and maintain the quality of the rice. Biopesticides can be an alternative to insecticides. They generally have high selectivity against pests, low toxicity, and are biodegradable. Another alternative to the use of pesticides could be ozone gas. There were already studies about the use of this gas for the removal of toxic substances in food3 but is important to t...