1 Citation
Additional file 1: Figure S1. Treatment of T. gondii with different drugs; 350 tachyzoites of Δku80 parasites were seeded into six-well plates covered with HFF cells, cultured with DMEM containing different drugs for 7 days, and then fixed and stained; the use of nifedipine at a concentration of 5 μM showed no significant difference compared with the control (DMSO/ ethyl alcohol); the antifungal agents voriconazole at 1.3 μM and clarithromycin at 3 μM both obviously affected the survival of the parasites; anticarcinogen ① KU-19, ③ WYE-132 (5 μM) and ④ SH5-07 (5 μM) all inhibited parasite growth, while ② Amg-319 (5 μM) showed no significant difference; coccidiostat metronidazole (5 μM) and toltrazuril (5 μM) did not differ significantly from the control, whereas dinitolmide (10 μM) and diclazuril (3 μM) obviously inhibited the survival of parasites.