1 Citation
Additional file 1: Fig. S1. Starvation preferentially sensitizes different breast cancer subtypes versus near normal cells to chemotherapy. a. In vitro treatment overview: cells were glucose/serum starved (STS) for 48 h (blue bar), drugs were added during the last 24h (red bar). b. MTT survival assays after 48 h treatment with STS with or without addition of doxorubicin (DXR) in near normal MCF-10A cells and the indicated breast cancer cell lines. Data are presented as mean survival percentage. *P ≤ 0.05. c. MTT survival assay after 48 h treatment with STS with or without 100 nM doxorubicin (DXR) in near normal MCF10A cells and the triple negative breast cancer cells MDA-MB-231, MDA-MB-468 and HS578. Data are presented as mean survival percentage. *P ≤ 0.05. d. MTT survival assays after 48 h treatment with STS with or without addition of cisplatin (CIS) in near normal MCF-10A cells and the indicated breast cancer cell lines. Data are presented as mean survival percentage. *P ≤ 0.05.