Figure 1. The screening flowchart of the study. Figure 2. The effect of rhGH on height, weight, IGF-1 level, insulin level and bone age among GHD and ISS children. A. GHD children; B. ISS children. NGHD = 33, NISS = 57. Compared with Baseline, ***P <0.001. Figure 3. Comparison of the effect of rhGH on height, weight, IGF-1 level and bone age between GHD and ISS children. NGHD = 33, NISS = 57. Compared with children with GHD, *P < 0.05.
Figure 4. The effect of rhGH in powder or liquid form on height, weight, bone age and IGF-1 level changes among GHD and ISS children. NGHD = 33, NISS = 57. Figure 5. The effect of rhGH on liver function, kidney function and thyroid function (ALT, AST, CREA, UA, FT3, FT4, TSH) and insulin level among GHD and ISS children. A. GHD children; B. ISS children. NGHD = 33, NISS = 57. Compared with Baseline, *P < 0.05, **P < 0.01, ***P < 0.001.
Figure 4. The effect of rhGH in powder or liquid form on height, weight, bone age and IGF-1 level changes among GHD and ISS children. NGHD = 33, NISS = 57. Figure 5. The effect of rhGH on liver function, kidney function and thyroid function (ALT, AST, CREA, UA, FT3, FT4, TSH) and insulin level among GHD and ISS children. A. GHD children; B. ISS children. NGHD = 33, NISS = 57. Compared with Baseline, *P < 0.05, **P < 0.01, ***P < 0.001.