The presentation provides a summary of past and ongoing activities in the area of temporal interference stimulation/modulation at the IT’IS Foundation. The following topics are covered:Pipeline for Personalized TI Stimulation Modeling: Exposure and ImpactPipeline for Personalized TI Stimulation Modeling: InvestigationsTI Exposure Quantities-of-InterestTI Safety White PaperTI Safety with ImplantsTI Planning ToolMethodological InnovationsUtilizing Implants for TI as Electrodes, Scatters etc.Exposure & Response OptimizationRelative Field Orientation and Heterogeneous Field MagnitudePhase ModulationInvestigated Mechanistic HypothesesImproving FocalityMeans of Exploiting Frequency Adding / Subtracting in Brain ComputationPeripheral Nerve Stimulation & TISpinal Cord Stimulation & TI