Structure of duplication regions: large (≥10 kb), high identity (≥95%) segmental duplications are shown between DUPA, DUPA', DUPB and DUPB' (green-striped blocks in the first row) as pairwise alignments (blue lines). Underlying duplicon mosaic structure (second bottom row) was defined using the program DupMasker [56]. The different colors represent the different cytoband locations for the ancestral loci of duplications (see the color key code below; NA, ancestral locus not determined) [56]. DUPA-DUPB' share fewer high-identity duplications compared to DUPA-DUPB (total aligned = 104.7 kb, average identity = 97.4%; Additional data file 6). The PBR and DBR are shown as red-striped blocks (third row). The proximal and distal breakpoint regions found in microdeletion cases (PBR' and DRB', fourth row), according to Mefford . [30], are shown as orange-striped blocks.Copyright information:Taken from "Hominoid chromosomal rearrangements on 17q map to complex regions of segmental duplication"http://genomebiology.com/2008/9/2/R28Genome Biology 2008;9(2):R28-R28.Published online 7 Feb 2008PMCID:PMC2374708.