Figure 3.2: Metacaspase subnetwork created using a BLAST threshold of E ≤ 10–45 clustered with CD-HIT at 80% sequence identity. This subnetwork was isolated from the whole C14 peptidase SSN. The network shows 1644 nodes, each representing a set of sequences with 80% sequence identity or higher. The BLAST threshold was selected to separate eukaryote sequences from prokaryote ones, while maintaining some connections between the type I/III and type II connected components. The colour scheme represents eukaryote taxa as indicated in the key.