Copyright information:Taken from "Use of adenoviral E1A protein to analyze K18 promoter deregulation in colon carcinoma cells discloses a role for CtBP1 and BRCA1"BMC Molecular Biology 2005;6():8-8.Published online 14 Apr 2005PMCID:PMC1087485. Luciferase activities are expressed relative to that obtained with the promoter construct alone in each cell line. Since the activities of all promoter constructs alone were adjusted to 100, they are all represented by a single pair of columns in each panel. The activity of these constructs relative to that of the wild type K18(80) promoter has been reported previously [22]. The structure of the various mutant forms of the K18(80) promoter is schematized in . Error bars represent the standard deviation of the mean of duplicate experimental points.