Copyright information:Taken from "The unusually large telomerase reverse-transcriptase localizes in a discrete compartment associated with the nucleolus"Nucleic Acids Research 2005;33(3):1111-1122.Published online 18 Feb 2005PMCID:PMC549419.© The Author 2005. Published by Oxford University Press. All rights reserved Average similarity of PfTERT to PkTERT (blue), Py TERT (green) and PbTERT (red). Similarity was computed in sliding windows of 20 amino acids over the multiple alignment. A score of 1 means that the 20 amino acids of the window are identical, whereas 0 indicates that the sequences do not share a single identical amino acid for a given position within the alignment (either because of substitutions or insertions/deletions). Above the graphics, the diagram indicates the in-scale position of all motifs in PfTERT protein. The asterisk points to an example of a region of PfTERT that is highly conserved among Plasmodium TERTs, but where no motif has yet been assigned. The lower panel shows the contribution of each Plasmodium TERT to the multiple alignments. Note that PyTERT and PbTERT sequences are not complete.