(A) RNAi efficiency verification of CYP6CP1 by qRT-PCR. The expression level of CYP6CP1 gene was down-regulated about 65Â % in Lab-DR4 mosquitoes microinjected with the siRNA404, compared with that in mosquitoes injected NC RNA. (B) Functional study of CYP6CP1 in Lab-DR4 strain. Mortalities of microinjected mosquitoes were observed after a 2Â h exposure to CDC bottles treated with deltamethrin (4Â mg/ml). The siRNA404 microinjected group had a higher mortality rate than the negative control. (TIF 1066 kb)